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How does hantavirus compare to Marburg virus?

Both hantavirus and Marburg virus can cause severe hemorrhagic disease, but they differ on key dimensions. Family: hantavirus is a Bunyavirales (Hantaviridae); Marburg is a filovirus (related to Ebola). Reservoir: hantavirus carried by rodents; Marburg by Egyptian fruit bats. Transmission between humans: hantavirus rare (Andes only, close contact); Marburg yes, through direct contact with body fluids. Mortality: hantavirus 30-40% (Andes HPS); Marburg 23-90% (average ~50%). Vaccine: no approved hantavirus vaccine; Sabin investigational Marburg vaccine in trials. Recent outbreaks: hantavirus MV Hondius (2026) and California (2025); Marburg Rwanda 2024, Tanzania 2025. Geography: hantavirus Americas + Eurasia; Marburg sub-Saharan Africa. Both are 'high consequence, low probability' threats requiring vigilance, not panic.

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Last update May 7, 2026 · ⚠ Not medical advice. Information is provided for awareness only; consult a physician for individual health questions.