What is the mortality rate of hantavirus?

Mortality varies sharply by virus species. Andes virus and Sin Nombre virus, which cause hantavirus pulmonary syndrome (HPS), have a historical case fatality rate (CFR) of 30-40%. The Eurasian variants causing hemorrhagic fever with renal syndrome (HFRS) — Puumala, Hantaan, Seoul — have lower CFR: Puumala 0.1-1%, Seoul ~1-2%, Hantaan 5-15%. The MV Hondius cluster involves Andes virus, the most lethal strain. The current CFR for this cluster is shown on the homepage Deaths KPI (deaths divided by confirmed cases) and updates hourly as new data is reported. There is no specific antiviral treatment; supportive intensive care (oxygen, ventilation, ECMO) is the standard of care and improves outcomes when initiated early.